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Is Benzoyl Peroxide really good for acne-prone skin?

May 26, 2023
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Benzoyl peroxide is a white crystalline powder that is soluble in organic solvents such as ethanol and acetone, but insoluble in water. It is synthesized by the reaction of benzoyl chloride with hydrogen peroxide in the presence of an acid catalyst. The resulting compounds are then purified and used as topical drugs. Benzoyl peroxide (BPO) was first synthesized in 1858; Benzoyl peroxide began commercial use in the United States in 1927; Benzoyl peroxide (BPO) is widely used in industry and medicine, and is included in the World Health Organization (WHO) list of Essential medicines. In the 60 years since its approval for acne treatment, benzoyl peroxide (BPO) has been recognized as a versatile and effective therapeutic agent. Due to its acne removal advantages, it is often favored by skin care brands, its added concentration is generally divided into 2.5%, 5.0%. Is Benzoyl Peroxide really good for acne-prone skin? How does it work? What are some popular related skin care products? Let’s explore together.

Benzoyl Peroxide

A hunter of comedogenic bacteria

Benzoyl peroxide is a potent antibacterial agent that works by releasing oxygen free radicals when it comes into contact with the skin. These free radicals penetrate the pores and kill Bacillus acnes, reducing the amount of acne damage and preventing new ones from forming. Benzoyl peroxide(BPO) is also effective against other bacteria that infect the skin, such as Staphylococcus aureus. The free oxygen radicals released by BPO can dissolve the cell wall and have a direct toxic effect on propionibacterium acnes, ultimately killing propionibacterium acnes. To avoid the inflammatory cascade that propionibacterium acnes triggers during the course of acne. BPO acts as an antibacterial agent through oxidation, rather than traditional “antibiotic” forms such as inhibiting protein synthesis or blocking metabolic processes. Because of this unique antibacterial way, bacterial resistance can be effectively avoided. Benzoyl peroxide(BPO) can kill bacteria in a variety of ways, thus improving the appearance of acne.

Benzoyl Peroxide

Anti-inflammatory and exfoliating helper

Benzoyl peroxide(BPO) also has anti-inflammatory properties. It can help reduce the redness associated with acne by reducing the production of pro-inflammatory cytokines in the skin. This can help reduce the appearance of pimples and prevent scarring. The chemotaxis and activation of neutrophils play an important role in acne inflammation. Propionibacterium acnes can produce a variety of bioactive substances, which have obvious chemotactic and activating effects on neutrophils, and eventually induce inflammatory infiltration and release of cytotoxic substances in acne lesions. The killing of reactive oxygen species released by BPO on propionibacterium acnes can terminate the process. Very small amounts of benzoyl peroxide (BPO) inhibit the release of inflammatory mediators by neutrophils. BPO has a dose-dependent inhibitory effect on neutrophils through apparent cytotoxicity, thus preventing the inflammatory response from occurring.

Compared with external use of retinol, Benzoyl peroxide(BPO) had A faster onset. Studies showed that with external use of BPO, the inflammation subsided in about 5 days at the earliest. Practice and research prove that Benzoyl peroxide(BPO) has a gentle exfoliating effect on the skin, helping to unclog pores and remove dead skin cells. Hyperkeratosis and abnormal keratosis are important causes of blockage of hair follicle ducts, and are the basis for the formation of microacne, acne and inflammatory acne. This can help prevent new acne lesions from forming and improve the overall texture and appearance of the skin. BPO can destroy the desmoid connection between keratinocytes and exfoliate the keratinocytes very superficial, thus facilitating the exfoliation of the abnormal accumulation of keratinocytes, thus relieving the blockage of the follicle duct opening and helping to improve acne. Studies have shown that BPO’s comedogenic properties are similar to salicylic acid and retinoic acid, but the onset time is faster than retinoic acid. BPO can also inhibit the biofilm formation of Propionibacterium acnes, reduce free fatty acid release, and avoid the accumulation of sebum and keratinocyte in the hair follicle duct.

Reduce sebum production and prevent antibiotic resistance

Sebum is an oily substance produced by the sebaceous glands in the skin. Excessive sebum production is one of the main causes of acne. Benzoyl peroxide(BPO) can help reduce sebum production by inhibiting the activity of the sebaceous glands. This can help prevent the formation of new acne lesions and improve the appearance of oily skin. Antibiotic resistance is a growing concern in the treatment of acne. Over time, Bacillus acnes can develop resistance to antibiotics, making them less effective. Benzoyl peroxide(BPO) doesn’t have this problem because it works by a different mechanism than antibiotics. As a result, Benzoyl peroxide(BPO) is used in combination with antibiotics to help prevent the development of resistance and enhance treatment effectiveness.

Benzoyl Peroxide

What are some popular related skin care products?

Benzoyl peroxide is a widely used ingredient in skin care, especially for acne-prone skin. Benzoyl peroxide is used in many forms in skin care products, including creams, gels, cleansers and spot treatments. It is primarily used as a topical treatment, applied directly to the affected area of skin. One of the most popular applications of benzoyl peroxide is in acne creams and gels. These products are formulated to deliver the active ingredient directly to the affected skin area. They are usually used once or twice a day, depending on the severity of the acne. Benzoyl peroxide creams and gels are often used as part of a comprehensive skin care routine that includes cleansing, toning and moisturizing. There are many well-known brands of benzoyl peroxide products in skin care products, such as:

  • Proactiv: Proactiv is a well-known skincare brand that focuses on treating acne. Their flagship product, Proactiv Solution, contains benzoyl peroxide as its primary active ingredient. It comes in a three-step system that includes a cleanser, toner, and treatment lotion. Proactiv products are popular for their effectiveness in combating acne breakouts and are endorsed by many celebrities.
  • Neutrogena: Neutrogena is a widely recognized brand that offers a range of skincare products. They have several benzoyl peroxide-based offerings, including the Rapid Clear Stubborn Acne Cleanser and the On-the-Spot Acne Treatment. Neutrogena products are known for their affordability and accessibility, making them a popular choice among consumers.
  • Clean & Clear: Clean & Clear is a brand that specifically targets young consumers dealing with acne-prone skin. Their products are designed to be gentle yet effective, and they offer a variety of benzoyl peroxide-based solutions. The Clean & Clear Persa-Gel 10 is a notable example, featuring a 10% concentration of benzoyl peroxide for maximum strength.
  • La Roche-Posay: La Roche-Posay is a French skincare brand that focuses on creating products for sensitive skin. Their Effaclar Duo Dual Action Acne Treatment is a popular choice among those seeking benzoyl peroxide-based solutions. It combines the acne-fighting properties of benzoyl peroxide with soothing ingredients to minimize irritation.
  • Murad: Murad is a brand known for its innovative skincare products and clinical approach to treating various skin concerns. Their Acne Control Rapid Relief Acne Spot Treatment contains benzoyl peroxide and aims to reduce the appearance of blemishes quickly. Murad products are often praised for their high quality and efficacy.
  • Acne.org: Acne.org is a brand created by Daniel Kern, an individual who struggled with acne and developed a line of products based on his personal experience. The Acne.org Treatment is a benzoyl peroxide gel that comes in a large size, offering a cost-effective option for individuals who require regular use.

How do I start using Benzoyl peroxide in my skin care business and daily care?

In daily skin care, you can choose to use Benzoyl peroxide as the main ingredient of skin care products. Through the use of regular products such as creams, toners and serums, after a period of use, you can see the obvious effects of this ingredient in terms of anti-inflammatory and acne removal, moisturizing and repairing the skin barrier.

When you want to start a related skin care brand business, you can start from the skin care set, we can help you develop different ingredients, different effects of skin care chain products. For example, starting with products such as mild acne removal skin care sets, with Benzoyl peroxid as the main ingredient, we can customize mature formulations and customize the packaging you need to help you produce high quality products and build brand value.

Benzoyl Peroxide
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