10 Exosome Skincare Manufacturers for Private Label Brands

Exosome skincare has garnered a lot of interest from beauty brands looking for something other than the traditional serums and creams. However, finding a manufacturer that advertizes exosome products is not the same as finding one that can explain the ingredient, formulate it properly, and help you sell the finished product in your target market.

This distinction is important.

Plant vesicle ingredients are used by some manufacturers . Others sell cell-culture-derived products, biotechnology-based delivery systems or formulations sold under the name exosome. These are not necessarily equivalent technologies and the supporting evidence can vary greatly.

I wouldn't choose an exosome skincare manufacturer just on the basis of the ingredient name.

As a manufacturer of skincare products, my first priority would be to understand the origin of the material, its characterisation, its stability in the intended formula and the claims which can be reasonably supported by the final product.

The model that is being produced is also important. A company selling a ready-to-use exosome serum for $250 is a different kind of brand than a biotech supplier that makes specialised ingredients for custom cosmetics.

For this guide, I examined ten manufacturers and suppliers with publicly documented exosome-related skincare products or OEM/ODM services. I reviewed their product lines, ingredient directions, production capabilities, minimum order quantities and where they might be appropriate for different stages of brand development.

My aim is to help you find possible manufacturing partners and understand the technical and regulatory questions you need to answer before you place an order.

How I Selected These Exosome Skincare Brands

For this list, I chose to focus on companies that have identifiable exosome-related skincare products, private label services or OEM/ODM development capabilities.

I wanted to see proof of real product formats, not just broad statements about regenerative biotechnology.

I also checked if the manufacturer explains its ingredient direction, provides formulation and packaging services and publishes useful commercial information.

A key limitation of this work is that the presence of an exosome product on a manufacturer’s list does not independently confirm that the ingredient contains purified, scientifically characterised extracellular vesicles.

The minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and.

10 Exosome Skincare Manufacturers at a Glance

The published quantities above relate to different manufacturing arrangements. A minimum for an existing formula should not be treated as the minimum for a fully customized exosome product.

1. XIRAN Skincare — China

Best for: Global brands developing personalised exosome-based skincare, multi-active serums and differentiated product textures.

XIRAN Skincare is a Guangzhou based skincare manufacturer. We provide private label, OEM/ODM, formulation development, packaging customisation and finished product manufacturing.

We have published range that contains Retinol & Exosome Dual-Capsule Serum with black truffle cell vesicle ingredients, NAD+, peptides and encapsulated retinoids. We also have PDRN Exosome Essential Oil Mist which is a dual layer jelly and oil formulation.

The products go in different directions in terms of development, one focusing on a visible capsule texture, the other on a shake-to-mix application experience.

We provide services for formula customisation, sampling, packaging coordination, testing and bulk production. Typical skincare projects start at 500~1,000 units per product, but customised packaging and special ingredients can alter that requirement.

XIRAN would be my choice for start-ups with a clear product concept and for growing brands that want a set of coordinated skin care products.

For an exosome-related project I would want the raw-material supplier to document the exact identity, source, and characterisation methods of the ingredient. The percentage of a commercial vesicle-containing ingredient is not necessarily the percentage of purified exosomes in the finished formula.

2. Moe's Group — United States

Best For: Private label and custom exosome-based cosmetic formulation for US-based skincare brands.

Moe’s Group is a privately held manufacturer and labeller of skin care products in Chatsworth, CA.

Its dedicated page on exosome manufacturing outlines the development and production of topical cosmetic formulas using ingredients derived from exosomes. The published product formats are serums, ampoules, essences, creams and masks.

The company provides services such as formulation, filling, labelling, packaging and custom product development. Also covers sourcing of ingredients and the need to differentiate between cosmetic formulations and those for clinical or injectable use.

I find the distinction helpful, because exosome skincare often employs the language of regenerative medicine, even if the eventual product is intended for regular retail cosmetics.

Moe’s Group sets out guidelines for the cosmetic development of ingredients derived from plants, marine sources and fermentation. However, I would request the actual raw-material specification, rather than assume that every ingredient marketed as an exosome contains the same type of vesicle.

The exosome page we reviewed doesn’t list a fixed MOQ for all projects.

I would recommend Moe’s Group to US startups that have sufficient development budgets and established brands that want a domestic custom manufacturing partner.

I'd check the chosen source of ingredient, availability of characterisation data, formula-development fees, sample requirements and minimum batch size before asking for a quote.

I would also want to know what finished product claims the available evidence could support and whether the proposed formula has a proper safety and stability testing plan.

3. Cosmiko — United Kingdom

Best for: UK startups and independent skincare brands looking for exosome-related existing formulas with relatively low minimum orders.

Cosmiko is a UK based private label cosmetics manufacturer providing off the shelf skin care formulations and branded packaging services.

Its published exosome range includes an Exosome Serum, Exosome Nite Cream and Exosome Eye Cream.

The company says its Exosome Serum has ingredients sourced from water radish kimchi and green tangerine. Included in the formula are ingredients like niacinamide, arbutin and Vitamin C, helping to position the product as a more well-rounded brightening and skin-conditioning option.

We recommend an airless bottle of 30 ml however Cosmiko has other packaging options.

A useful commercial detail is its published 250-unit minimum order for the Exosome Serum. Similarly, the Nite Cream and Eye Cream pages indicate that the minimum starting order quantity for their existing formulas is 250 units.

That makes Cosmiko interesting to explore for a brand that wants to test an exosome-related range without committing to several thousand finished products right away.

I think it would be particularly relevant to UK ecommerce businesses, independent beauty founders and small professional skincare brands.

Before I order I would ask for the full INCI list and the actual technical documentation of the supplier of the ingredients and clarification of what the term exosome means in the proposed formula.

I would also ask about the testing records and regulatory paperwork that they have available for the product they have chosen, particularly if they are looking to sell outside the UK.

4. Laboratori Italiani — Italy

Best for: Brands looking for Italian manufacturing, plant-derived exosome concepts and small existing-formula production quantities.

Laboratori Italiani is an Italian private label manufacturer of skin care products providing ready cosmetic formulas, custom formulation, production and packaging support.

Its catalogue includes an Exosome Serum, reference STEXO30OS.

This product is a blend of plant-derived exosome ingredients along with extracts from apple, watermelon and grapefruit, the company says. The formula also contains a biomimetic peptide and low molecular weight hyaluronic acid.

The reference format published is a 30ml serum but the company says brands can choose different packaging and use their own labels and artwork.

This existing formula is published by Laboratori Italiani at a minimum of 500 pieces per reference.

I would look at the company for a European skincare startup that wants to start off with a documented catalogue concept rather than commission a new formula off the bat.

It might also appeal to growing brands that appreciate Italian manufacturing and need assistance with European cosmetic documentation.

The company advertizes services related to Cosmetic Product Safety Report, Product Information File and CPNP notification.

But I would still ask which documents are covered by the quoted service and which responsibilities still remain with the EU Responsible Person of the brand.

For the exosome ingredient itself, I would ask for its INCI designation, raw-material specifications and evidence of characterisation.

Cellular renewal is a marketing term used by the supplier, and should not be used directly in the finished product without proper substantiation.

5. Unicare Biotech — Taiwan

Best for: Formulation-driven skincare brands that want to explore new exosome related textures, essences and specialised ODM products.

Unicare Biotech is a Taiwanese ODM manufacturer of skincare products that provides formulation development and finished product manufacturing.

In its Rejuvenation public portfolio, it discusses exosome technology and presents several skincare development concepts, including exosome-related essences and facial mist presentations.

The company also has an Exosome Dual Gold Revitalising Essence in its product video portfolio.

One thing I like is that Unicare clearly states that the products on its Rejuvenation page are concepts by ODMs and not consumer-facing products.

That distinction is important to a brand owner. It means that the portfolio is meant to show development potential, although the exact ingredient and production setup still needs to be confirmed.

I would recommend Unicare to an established or growing skincare brand looking for more differentiated textures or a wider premium skincare collection.”

The pages reviewed do not provide a uniform MOQ for exosome-related projects.

I would like to request separate quotes for each intended format such as serum, mist or other delivery systems.

The first technical question should be on the ingredient itself: whether it is a characterised extracellular vesicle preparation, a plant-derived vesicle ingredient or a different biotechnology-based cosmetic material.

I would also ask about formulation stability, packaging compatibility, safety data available, and the specific site at which the product is manufactured.

6. CellSource — Japan

Best for: Speciality Japanese-market projects needing detailed ingredient provenance, biotechnology expertise and regulatory assessment.

CellSource is a Japanese biotechnology company involved in regenerative medicine and cosmetic ingredients.

Its consumer business page lists CellSource Exosome® as an ingredient derived from human adipose-derived mesenchymal cells.

The company also offers cosmetic OEM/ODM services based on its exosome materials. Its published process includes product consultation, concept development, sample preparation, container selection, quoting, production and delivery.

This is a different manufacturing proposition to suppliers of plant-derived vesicle serums.

I would not assume that the ingredient is interchangeable with a botanical extract, or that it is suitable for all international cosmetics markets.

CellSource doesn’t have a uniform cosmetic OEM MOQ on the page we viewed.

It may be worth looking into the company if you have a specialised project in a market where the material and use have been evaluated under the applicable laws.

However, cells, tissues or products of human origin are excluded by EU cosmetic regulation Annex II, entry 416. Therefore I would not include this human-derived ingredient in an EU cosmetic product brief.

Before entering into a contract with CellSource, I would require a legal review of the receiving market, and details on the source of the ingredients, donor screening, characterisation, safety and traceability.

Just because an ingredient or OEM service is Japanese does not guarantee it has international regulatory acceptance.

7. Hong Shin Cosmetics — Taiwan and South Korea

Best for: New skincare brands seeking customised exosome ampoules, serums and freeze dried formulation concepts.

Hong Shin Cosmetics provides private label & OEM/ODM development for skincare brands looking for Asian manufacturing.

Its exosome ingredient page lists plant-derived and biotechnology-based ingredients for topical cosmetic formulations.

The company’s main formats are serums and ampoules, but where formulation stability dictates otherwise, it also talks lyophilised systems with a separate activator.

It also describes possible combinations with PDRN, peptides and niacinamide.

I find Hong Shin interesting in the sense that there is a difference between ingredient development and the actual site.

The company says its exosome-related development uses South Korean capabilities, but the described program is manufactured and quality-controlled in Taiwan.

On its exosome page, minimums are 1,500 units per SKU on Taiwan production lines and 3,000 units per SKU on Korean lines, with a projected lead time of 10 to 12 weeks.

I’d look at Hong Shin for a growing brand with a defined product brief and realistic sales forecast.”

Before I place an order, I would want to know where the factory is located, where the ingredients for the formula come from, and whether the proposed order is using an existing serum platform or a full custom development.

For freeze-dried products, I would also need a clear reconstitution procedure, stability data, packaging specifications and an assessment of the intended use of the final product.

8. Dermat India — India

Best for: Indian skincare startups and growing brands looking to go into private label exosome-related serums.

Dermat India is a private label and OEM/ODM skincare manufacturer based in Gurugram, India.

On the dedicated Exosome Serum page, you will find custom formulation, ingredient development, packaging choice, labelling, and bulk manufacturing support.

The company also talks about pairing exosome-related ingredients with peptides, hyaluronic acid and vitamins.

Dermat India describes flexible minimum order quantities for both small and larger projects, but the page reviewed does not give a specific numerical MOQ.

So I would ask for a written minimum for the actual formulation and packaging instead of a general low MOQ statement.

“I can see Dermat India becoming the supplier of choice for Indian DTC brands, or for established beauty businesses that want to try out a niche serum concept.

However, the company's public marketing is full of strong statements about cellular repair, regeneration and other biological effects.

I would not assume those claims are appropriate in every market for a finished cosmetic.

Before going ahead, I would want to know the full identity, source, technical specification and evidence for use of the ingredient in the proposed product.”

The manufacturer should also indicate whether the formulation is intended for use only as a topical cosmetic.

For brands exporting to the United States or Europe, I would establish market-specific safety, labelling and claim requirements prior to approving production.

9. QiaoMei Cosmetics — China

Best for: Brands looking for OEM/ODM manufacturing from China with custom skincare formulation and packaging support.

QiaoMei Cosmetics is a China-based cosmetics manufacturer that provides private label and OEM/ODM services in skincare, hair care, body care and makeup.

Its website also has a page on exosome-related skincare development, along with general formulation, manufacturing, packaging design and finished product services.

The company describes an internal R&D team and manufacturing capabilities for a range of cosmetic product formats.

For a beauty brand looking into an exosome-inspired serum or a more general skincare line, QiaoMei is one manufacturer to consider for an initial supplier inquiry.

It claims generic OEM/ODM information with minimum orders of 1,000 units.

But I didn’t find any documented exosome specific MOQ for a certain formula. The actual requirement should be established in a written quotation.

For startups and growing brands that want to coordinate formulation and packaging with a Chinese manufacturing supplier, I would look at QiaoMei.

The first thing I would check is the definition of the ingredient.

Its exosome information includes human cell-derived extracellular vesicles and plant-derived biological mechanisms and materials. However, these descriptions should not be considered as evidence that the ingredient was used in a proposed retail cosmetic.

Before sampling I would ask for written confirmation of source, INCI, characterisation data, target-market suitability and claims supported by the finished formulation.

10. CNB International — South Korea

Best for: Korean skincare & pro-beauty brands looking to explore exosome, PDRN, collagen and peptide combinations.

CNB International is a South Korean beauty company with a public portfolio of products targeting advanced skin care and professional aesthetic concepts.

On the official website, there are several exosome-related products, such as Selastin Exo Plus, Lacto Exo Colla Soothing Cream, and formulas that contain a mix of exosome-related ingredients with PDRN, collagen, peptides, and NAD+.

Plant-derived ingredients related to Cica and Camellia are said to be included in Selastin Exo Plus.

The company also says on its corporate information page that it runs an integrated OEM/ODM business model.

That makes CNB worth checking out for brands that want a more complex ingredient-led skincare concept, especially those already familiar with Korean professional-beauty products.

But I wouldn't assume that every formula in their catalogue is available for normal retail private label.

There is no uniform MOQ for exosome skincare manufacturing published on the official pages reviewed.

I would like to ask about the products that could be adapted for private label, whether CNB manufactures them directly and where the proposed batch would be produced.

I would also confirm whether the product is intended for regular use as a cosmetic on the skin or in a professional treatment setting.

For international markets, review the ingredient source, formulation classification, safety documentation, and permitted claims before ordering samples.

Which Exosome Skincare Manufacturer Fits Your Brand?

After comparing these manufacturers, I would narrow the shortlist according to the brand's target market and product requirements rather than choose by country alone.

I would treat this as a starting shortlist, not a final purchasing recommendation.

A supplier with a lower MOQ may be suitable for testing an existing product, while a manufacturer with specialized formulation capabilities may be more useful for an established brand developing an exclusive formula.

In the exosome category, though, the first decision should concern the material itself.

What To Consider Before Choosing An Exosome Skincare Manufacturer?

Exosome skincare demands a different level of questioning to your supplier than an average moisturising serum.

I would look at what the ingredient is, how it behaves in the final formulation and what evidence exists to justify the product’s intended positioning.

What’s the Source of the Exosome Ingredient, Really?

“Exosome” alone is not enough to identify a cosmetic raw material.

A supplier may be talking about extracellular vesicles from mammalian cells, plant vesicle-like particles, bacterial vesicles, an ingredient from fermentation, or a delivery system marketed with language related to exosomes.

These materials should not be considered as interchangeable.

I would ask the supplier for their official raw-material name, full INCI name, source, method of manufacture and technical specification.

With plant-derived ingredients I would also want to know whether the supplied material is an isolated vesicle or a more generalised extract with multiple components.

If that distinction isn't clear, I wouldn't build a finished product marketing claim on it.

How Has the Material Been Characterised?

I would not take a single particle size value as evidence for exosome identity.

Depending on the material and the claims being made, characterisation of extracellular vesicles may require several complementary methods.

Useful scientific reference for terminology, preparation, separation and characterisation is provided by the MISEV2023 guidelines.

For a commercial ingredient I would ask the supplier about their methods, what the measurements mean, and whether they have results on relevant production batches.

Also, need to clarify an ingredient that is sold at a certain concentration. A formula with 3% of a raw materialcontaining a vesicle doesn't mean it contains 3% pure extracellular vesicles.

This is an important difference for formulation and marketing as well.

Can the manufacturer prove stability of the formula?

The raw material may have enough characterisation but still has to be suitable for the final skincare formula.

A serum, cream, mist and freeze dried product can expose ingredients to different processing and storage conditions.

I would like to know the effect of temperature, pH, mixing, packaging and storage on the material to be used.

The testing program should also cover the general physical, chemical and microbiological stability of the finished product.

If a dual-component product, the manufacturer should explain how it is prepared, the life after mixing and what instructions the consumer needs.

“I wouldn’t make the claim that a formula would have exosome activity throughout its shelf life without hard evidence to back it up.

4. Is the Ingredient Suitable for Your Target Market?

Does the ingredient fit your target market?

This is one of the most important decisions in the purchase process.

“The FDA’s consumer alert about regenerative medicine products for the United States says there are no exosome products that are FDA approved.”

This is especially the case for exosome products that are marketed for medical or therapeutic uses. In general, ordinary cosmetic products do not require FDA premarket approval, but they must comply with the applicable cosmetic laws.

If a product claims to treat disease, heal tissue or alter the structure or function of the body, it may be regulated as a drug, not as a typical cosmetic.

Regulation (EC) No 1223/2009 sets out Annex II restrictions for European Union cosmetics, including entry 416, which concerns cells, tissues or products of human origin.

I would not accept a human derived exosome ingredient for an EU cosmetic project.

Plant-derived ingredients still need their own safety assessment, regulatory review and appropriate claims evidence.

Final Thoughts: Choose the Ingredient First, Then the Manufacturer

The use of exosomes in skincare may be an interesting opportunity for brands to explore new cosmetic ingredients and product formats, but a careful technical evaluation is also needed.

I would not choose a manufacturer just because it has the newest exosome serum or boasts a particularly high concentration.

More useful questions include: what is the actual ingredient, where did it come from, how is it characterised, what does it do in the finished formula, and could you responsibly market the product in the country you intend to sell it?

If you’re launching a brand, an off-the-shelf plant-based formula may be an easier option than a complicated custom project. A growing skincare company with specialised delivery systems, premium textures and coordinated formulations may warrant additional development.

Anyway I'd start with a clear brief and compare manufacturers against the same requirements.

XIRAN Skincare is a private label and custom skincare manufacturer for products developed based on biotechnology-inspired ingredients, peptides, retinoids and other skincare actives.

Brands can check out our custom cosmetic formulation services, and packaging customisation options for a new product in the making.

If you are considering starting a skincare project based on exosomes, please contact our team with your intended ingredient source, product format, target market, packaging requirements and expected quantity.

The first step isn’t just picking a formula called “Exosome Serum.” It’s about determining exactly what you’re looking to produce, and if the evidence out there supports the product your brand wants to sell.